Tablet for Dogs and Cats
COMPOSITION:
300 mg contains active substances:
Megestrol acetate – 5 mg;
Additional ingredients: powdered sugar, calcium carbonate, sodium carboxymethylcellulose, polyvinylpyrrolidone, flavor, magnesium stearate, sucram.
DESCRIPTION:
Cylindrical tablets with a flat surface, scored and beveled, white or light gray color with specific smell and marbling (inclusions) allowed on the surface.
PHARMACOLOGICAL CHARACTERISTICS:
Megestrol acetate is a synthetic progestogen that affects the hypothalamic-pituitary system and blocks the secretion of gonadotrophins (follicle-stimulating and luteinizing hormones). This results in delayed follicle maturation in females and blocked testosterone synthesis in males, terminating estrus and sexual attraction. The drug has two main actions:
- Anty-gonadotrophic activity: Inhibits gonadotropin secretion and delays ovulation, delaying estrus.
- Progestogen action: Directly affects the endometrium of the uterus, activating the secretory phase and slowing embryo implantation, enhancing contraceptive properties.
APPLICATION:
Orally for dogs and cats to:
- Prevent or terminate estrus in females
- Prevent unwanted pregnancy in females
- Suppress libido in males
DOSAGE & ADMINISTRATION:
Administer orally with food or directly to the root of the tongue.
Female Cats:
- Prevention of estrus: 1 tablet daily for 10-14 days. Estrus occurs within 14 days after discontinuation.
- To stop estrus: 1 tablet daily for 3-5 days from signs of sexual arousal.
- Contraceptive: 3 tablets within one day after mating.
Female Dogs:
- Prevention of estrus: 1 tablet per 10 kg body weight every 14 days. Estrus occurs within 21 days after discontinuation.
- To stop estrus: 1 tablet per 10 kg body weight daily for 7 days from signs of sexual arousal.
- Contraceptive: 2 tablets per 5 kg body weight daily for 2 days after mating.
Male Cats:
- Sedation during sexual arousal: 1 tablet daily for 3-5 days.
Male Dogs:
- Sedation during sexual arousal: 1 tablet per 10 kg body weight daily for 5 days.
CONTRAINDICATION :
- Do not use in animals with genitourinary system diseases, tumors, immature, pregnant, or lactating animals.
- Do not use after the onset of estrus for more than 3 days or in young animals during their first estrus.
PRECAUTIONS:
- Prolonged use may alter behavior, development of breasts, increase appetite, and associated weight gain.
PACKAGING :
Blister packs containing 10 tablets in cartons
STORAGE:
- Store in a dark, dry place at temperatures between 5°C and 25°C.
- Do not store with food.
FOR VETERINARY USE ONLY!