Drops for Dogs
DESCRIPTION :
Oily liquid from light gray to light yellow color with a specific smile.
COMPOSITION:
1 ml of drug contains active substances:
Megestrol acetate – 5 mg
Additional ingredients: polyethylene glycol-400 up to 1 ml
CLINICAL PHARMACOLOGY
Megestrol acetate is a synthetic progestogen, which affects the hypothalamic-pituitary system and blocks the allocation of animals gonadotrophins (follicle-stimulating and luteinizing). With a lack of these hormones in the blood of delayed maturation of follicles in the ovaries of females and males testosterone synthesis is blocked, resulting in terminated estrus and sexual attraction to animals. In dogs and cats drug reduces sexual activity and related behavior.
The mechanism of action of megestrol acetate has two main areas of impact on the body: anty-gonadotrophic activity manifested in inhibiting the secretion of gonadotropin hormones and delay ovulation, which is the result of delays clinically estrus; progestogen action is a direct effect on the endometrium of the uterus, which activates the secretory phase, which slows down the implantation of the embryo, increasing contraceptive properties of the drug.
APPLICATION :
Orally for dogs to prevent or terminate oestrus in female dogs, prevention of unwanted pregnancy in female dogs, as well as to suppress libido in males dogs.
DOSAGE :
Orally with food or force directly to the root of the tongue
FEMALE DOGS:
– To prevent estrus – 1 ml of the Preparation per 10 kg of body weight every 14 days. After discontinuation of the drug estrus occurs within 21 days;
- To stop oestrus – 1 ml of the preparation per 10 kg of body weight for 7 days (from the time of display signs of sexual arousal);
- As a contraceptive – 2 ml of the preparation per 5 kg of body weight daily for 2 days after mating;
MALE DOGS:
– For sedation during sexual arousal – 1 ml of preparation per 10 kg of body weight daily for 5 days.
CONTRAINDICATION :
Do not use the drug with diseases of the genitourinary system, tumors, to immature, pregnant and lactating animals.
Do not use the drug after the onset of estrus was more than 3 days, and young animals during their first estrus because of the difficulty determining the beginning of the cycle.
PRECAUTIONS:
Prolonged use of the drug may change the nature, development of breasts, increase appetite, and associated with its body weight.
PACKAGING:
Plastic vials and/or bottles (glass or plastic with drip-stopper) of 1, 2, 4 ml that nested in cartons.
STORAGE:
Dark, inaccessible for children place at a temperature from 5°C to 25°C.
Do not store together with food, drinks.
FOR VETERINARY USE ONLY!