CEFTIFUR 50

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COMPOSITION:

1 ml of product contains active agent:

ceftiofur hydrochloride – 50 mg.

CLINICAL PHARMACOLOGY:

Ceftiofur hydrochloride, a third-generation cephalosporin antibiotic, exhibits a wide spectrum of bactericidal activity against both gram-positive and gram-negative bacteria, including strains that produce beta-lactamases. It also targets certain anaerobic bacteria such as Escherichia coli, Pasteurella haemolytica, and Salmonella cholerasuis, among others. Ceftiofur’s mechanism of action involves inhibiting bacterial cell wall synthesis.

APPLICATION:

Cattle: Ceftiofur is used to treat a range of conditions including respiratory diseases (such as pneumonia and bronchopneumonia), postpartum endometritis, mastitis, necrobacillosis, arthritis, sepsis, and other bacterial infections susceptible to ceftiofur.

Pigs: Ceftiofur is employed to treat respiratory diseases and other bacterial infections susceptible to ceftiofur.

DOSAGE:

Cattle: administer ceftiofur subcutaneously once a day at a dosage of 1 ml per 50 kg Body Weight Gain (BWG), equivalent to 1 mg of ceftiofur hydrochloride per 1 kg BWG. The treatment duration varies:

  • Respiratory diseases: 3-5 days
  • Necrobacillosis: 3 days
  • Endometritis: 5 days

Pigs : administer ceftiofur intramuscularly once a day at a dosage of 1 ml per 16 kg BWG, equivalent to 3 mg of ceftiofur hydrochloride per 1 kg BWG, for 3-4 days.

CONTRAINDICATIONS:

  1. Hypersensitivity: Avoid in animals with known hypersensitivity to ceftiofur or other beta-lactam antibiotics.
  2. Mixing: Do not mix with other drugs in the same syringe.
  3. Renal Impairment: Avoid use in animals with impaired renal function.
  4. Resistance: Do not use in cases of resistance to cephalosporins or other beta-lactam antibiotics.
  5. Route of Administration: Do not administer intravenously.

WITHDRAWAL:

The withdrawal periods for ceftiofur are as follows:

  • Meat Consumption: 8 days for cattle and 5 days for pigs after the last application of the drug.
  • Milk and Eggs Consumption: Not Applicable (N/A).

Any meat obtained before the withdrawal period deadline must either be fed to unproductive animals or utilized, as determined by a veterinarian.

PACKAGING:

Avilable in glass vial, 50, and 100 ml.

STORAGE :

Store the product in a dry, dark place inaccessible to children at a temperature ranging from 5°C to 25°C. After the first opening, the product remains usable for up to 28 days.

FOR VETERINARY USE ONLY!