COMPOSITION:
1 ml contains active substances:
Sulfadimethoxine sodium salt – 300 mg;
Sulfadiazine sodium salt – 300 mg;
Trimethoprim – 120 mg.
PHARMACOLOGICAL CHARACTERISTICS:
The drug containing sulfonamides and trimethoprim blocks two successive stages of folic acid biosynthesis in bacterial cells, inhibiting bacterial growth and propagation effectively. The combination of sulfonamides and trimethoprim extends its antimicrobial spectrum against a wide range of gram-positive and gram-negative bacteria, including Staphylococcus spp., Streptococcus spp., E. coli, Salmonella spp., and many others. It also affects some protozoa. This combination reduces the likelihood of resistant strains.
APPLICATION:
Used to treat gastrointestinal, respiratory, and genitourinary diseases in various animals, including cattle, sheep, goats, horses, pigs, rabbits, dogs, cats, and poultry. It addresses conditions like gastritis, enteritis, bronchopneumonia, postpartum sepsis, mastitis, and more, caused by bacteria susceptible to sulfadimethoxine, sulfadiazine, and trimethoprim.
DOSAGE & ADMINISTARTION:
Administered intramuscularly as follows:
- Cattle, Sheep, Goats, Horses, Pigs: 0.6-0.8 ml per 10 kg of body weight
- Dogs, Cats: 0.1-0.15 ml per 1 kg of body weight
- Poultry (Chickens, Turkeys, Ducks, Geese), Rabbits: 0.1 ml per 1 kg of body weight
Repeat doses 3-5 times at intervals of 24-36 hours, with a recommended treatment course of 5 days. For young and small animals, inject no more than 10 ml at one site, and for adult animals, not more than 20 ml. Slow intravenous or intra-arterial injection is permissible for large animals.
PRECAUTIONS:
Avoid diluting the drug with novocaine. Use caution in goats due to their hypersensitivity to sulfonamides. Meat consumption is permissible after 10 days, while milk and eggs can be consumed after 4 days post-treatment. Dispose of or feed products to unproductive animals based on veterinary advice.
PACKAGING :
Available in glass bottles with rubber plugs under aluminum caps, accompanied by sterile 0.9% sodium chloride.
STORAGE:
In a dry, dark place at temperatures between 0°C to 25°C. Once mixed with the solvent, use the solution within a day or within three days if refrigerated.
FOR VETERINARY USE ONLY!