PRESENTATION
100 mL sterile multi-dose glass vial
COMPOSITION
Thiamine hydrochloride 125 mg/mL
ACTIONS
Vitamin B1 Injection provides Thiamine which is essential for the metabolism of carbohydrates and energy production for all cells. Thiamine is crucial in the breakdown of pyruvic and lactic acid, particularly in hard-working muscles. It is necessary for the coenzyme involved in the breakdown of glucose for energy. In situations where carbohydrates are the major energy source or when glucose is added to the diet, the need for Thiamine significantly increases.
Thiamine, together with Vitamin B6, is vital in the metabolism of proteins and amino acids. It affects all tissues, with the nerves, stomach, and heart being the most sensitive. Free Thiamine is not storable in the body and can be quickly absorbed from the intestine, blood, or injection sites.
Thiamine is water-soluble and needs regular supplementation, especially for hard-working animals, as dietary intake may not be enough. It is found in meat and cereal products and can be produced in small amounts in the gut. Thiamine in food is destroyed by cooking, with beef losing up to 75% of its Thiamine when cooked. High doses of Thiamine can help calm nervous or overexcitable horses. Clinical signs of Thiamine deficiency include fatigue, muscle weakness, loss of appetite, and increased heart rate. These symptoms can be linked to increased levels of lactic and pyruvic acids in the tissue, affecting nerve cells that are particularly dependent on carbohydrate metabolism, especially during hard work.
DOSAGE AND ADMINISTRATION
Horses: Give 5 – 10 mL by intramuscular injection twice weekly, or as advised by a veterinary surgeon.
Dogs: Give 1 – 2 mL by intramuscular injection twice weekly, or as advised by a veterinary surgeon.
STORAGE
Store below 25°C (Air Conditioning). Protect from light.
NOTES
Vitamin B1 is known for its calming effect on animals when given in large doses. Injecting Vitamin B1 prior to situations that may excite horses or dogs can help calm them down. Horses on high grain diets may benefit from additional Vitamin B1.
WITHDRAWAL PERIOD
None