for Injections
DESCRIPTION:
A homogeneous, clear solution from light yellow to yellow color
COMPOSITION :
1 ml contains active substances:
Ivermectin – 10 mg;
Additional substances: – up to 1 ml
PHARMACOLOGICAL CHARACTERISTICS:
Ivermectin is an avermectin anthelmintic drug. The substance increases the release of gamma-aminobutyric acid (GABA) in presynaptic neurons. GABA is a Universal Brake neurotransmitter that blocks postsynaptic stimulation of neighboring neurons in nematodes. By stimulating the release of GABA ivermectin causes paralysis and the death of parasites. After subcutaneous administration, the drug has the highest capacity for absorption.
Ivermectin is metabolized in the liver by oxidation processes, secreted mainly in the feces. Less than 5% of the drug is excreted in the urine
APPLICATION:
Prevention and treatment of diseases of cattle, sheep, goats, pigs, dogs caused by:
Cattle: gastrointestinal nematodes – Ostertagia ostertagi, O. lyrata, Trichostrongylus axei, Trichostrongylus Columbiformes, Haemonchus placei (including third stage larvae), Nematodirus spp. (mature forms); pulmonary nematodes – Dictyocaulus viviparus (adults and fourth larvae stage); itch tick – Sarcoptes Bovis, Psoroptes Bovis; gadfly (in larvae phase) – Hypoderma lineatum, H. Bovis; lice – Linognathus vituli, Haematopinus eurysternus, Solenopoles capillatus; louse – Bovicola Bovis;
Sheep and Goats: gastrointestinal nematodes – Haemonchus contortus, (mature and the third and fourth larvae stage), Trichostrongylus vitrinus (mature forms), T. Columbiformes (mature and fourth-stage larvae), Nematodirus filicollis (mature and fourth-stage larvae), Oesophagostomum colombianum, O. venulosum (mature forms), Charbetia ovina (mature forms), Trichuris ovis (mature forms); pulmonary nematodes – Dictyocaulus filaria (mature and fourth-stage larvae), Protostronlylus spp. (mature forms); itch tick – Sarcoptes scabiei, Psoroptes communis (var. Ovis); nasopharyngeal gadflies – Oestrus ovis (all larval stages);
Pigs: gastrointestinal nematodes – Ascaris suum, Hyostrongylus rubidus (mature and fourth-stage larvae), Oesophagostomum spp., Strongyloides ransomi (mature forms); pulmonary nematodes – Metastrongylus spp. (mature forms); lice – Haematopinus suis; itch tick – Sarcoptes suis.
Dogs: nematodes – Dirofilaria immitis, D. repens, Toxascaris leonine, Toxocara Canis, Uncinaria stenocephala, Ancylostoma caninum; ticks – Sarcoptes Canis, Demodex Canis, Otodectes cynotis; lice – Linognathus setosus.
DOSAGE:
The drug is applied once only subcutaneously at doses:
Cattle, Sheep, and Goats: 1 ml per 50 kg of body weight (0.2 mg ivermectin per 1 kg of body weight) injected into the area of the shoulder-blade.
Pigs: 1 ml per 33 kg of body weight (0.3 mg ivermectin per 1 kg of body weight) injected into the middle section of the neck.
Dogs: 0.1-0.2 ml per 5 kg of body weight (0.2-0.4 mg ivermectin per 1 kg of body weight).
CONTRAINDICATIONS:
Do not administer the drug intravenously or intramuscularly.
Do not apply to cows, goats, and lactating ewe in 28 days before the delivery.
Do not use it on dogs of breeds Collie, Bobtail, and their hybrids, or small breeds of dogs and puppies under 3 months.
Do not apply it to exhausted and suffering animals from infectious diseases.
Follow the exact dosage for pigs.
PRECAUTIONS:
Meat consumption is allowed after 28 days from the last administration of the drug.
Received by the deadline meat is fed to unproductive animals or utilized, according to the conclusion of the doctor of veterinary medicine.
PACKAGING:
Ampoules of brown glass closed with a rubber stopper under an aluminum cap of 10, 20, 50, 100, and 200 ml.
STORAGE:
A dry, dark place, away from children at a temperature from 5°C to 25°C.
The drug is stored separately from food, beverages, including animal feed.
FOR VETERINARY USE ONLY!