{"id":587,"date":"2020-07-18T11:41:58","date_gmt":"2020-07-18T11:41:58","guid":{"rendered":"https:\/\/knight-pharma.com\/web\/?page_id=587"},"modified":"2024-06-14T02:39:13","modified_gmt":"2024-06-14T02:39:13","slug":"powersex-d-drops","status":"publish","type":"page","link":"https:\/\/knight-pharma.com\/web\/powersex-d-drops\/","title":{"rendered":"POWERSEX D DROPS"},"content":{"rendered":"\n

Drops for Dogs<\/strong><\/mark><\/p>\n\n\n\n

<<PREVIOUS |<\/a>| NEXT>><\/a><\/p>\n\n\n

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DESCRIPTION :<\/span><\/strong><\/p>\n\n\n\n

An oily liquid ranging from light gray to light yellow color with a distinct odor.<\/p>\n\n\n\n

COMPOSITION:<\/span><\/strong><\/p>\n\n\n\n

Each 1 ml of the drug contains:<\/p>\n\n\n\n

    \n
  • Megestrol acetate: 5 mg<\/li>\n\n\n\n
  • Additional ingredients: Polyethylene glycol-400 up to 1 ml<\/li>\n<\/ul>\n\n\n\n

    CLINICAL PHARMACOLOGY<\/span><\/strong><\/p>\n\n\n\n

    Megestrol acetate, a synthetic progestogen, affects the hypothalamic-pituitary system, blocking the release of gonadotrophins (follicle-stimulating and luteinizing hormones). This leads to delayed follicle maturation in the ovaries and inhibits testosterone synthesis in males, resulting in suppressed estrus and sexual attraction.<\/p>\n\n\n\n

    In dogs and cats, the drug reduces sexual activity and associated behaviors.<\/p>\n\n\n\n

    Its mechanism of action includes:<\/p>\n\n\n\n

      \n
    • Antigonadotropic activity: inhibiting gonadotropin hormone secretion and delaying ovulation, thus suppressing estrus.<\/li>\n\n\n\n
    • Progestogenic action: directly affecting the uterine endometrium, activating the secretory phase, delaying embryo implantation, and enhancing contraceptive properties.<\/li>\n<\/ul>\n\n\n\n

      APPLICATION :<\/span><\/strong><\/p>\n\n\n\n

      Orally administered to dogs for:<\/p>\n\n\n\n

        \n
      • Preventing or terminating estrus in female dogs<\/li>\n\n\n\n
      • Preventing unwanted pregnancy in female dogs<\/li>\n\n\n\n
      • Suppressing libido in male dogs<\/li>\n<\/ul>\n\n\n\n

        DOSAGE :<\/span><\/strong><\/p>\n\n\n\n

        Administer orally with food or directly to the root of the tongue.<\/p>\n\n\n\n

        Female Dogs:<\/strong><\/p>\n\n\n\n

          \n
        • To prevent estrus: 1 ml of the preparation per 10 kg of body weight every 14 days. Estrus typically resumes within 21 days after discontinuation.<\/li>\n\n\n\n
        • To stop estrus: 1 ml of the preparation per 10 kg of body weight for 7 days (upon the onset of signs of sexual arousal).<\/li>\n\n\n\n
        • As a contraceptive: 2 ml of the preparation per 5 kg of body weight daily for 2 days after mating.<\/li>\n<\/ul>\n\n\n\n

          Male Dogs:<\/strong><\/p>\n\n\n\n

            \n
          • For sedation during sexual arousal: 1 ml of preparation per 10 kg of body weight daily for 5 days.<\/li>\n<\/ul>\n\n\n\n

            CONTRAINDICATION :<\/span><\/strong><\/p>\n\n\n\n

            Avoid use in animals with genitourinary system diseases, tumors, immature, pregnant, or lactating animals. Also, avoid use after estrus onset for more than 3 days and in young animals during their first estrus due to cycle timing difficulties.<\/p>\n\n\n\n

            PRECAUTION: <\/strong><\/p>\n\n\n\n

            Prolonged use may alter breast development, increase appetite, and lead to weight gain.<\/p>\n\n\n\n

            PACKAGING:<\/span><\/strong><\/p>\n\n\n\n

            Available in plastic vials and\/or bottles (glass or plastic with a drip-stopper) of 1 ml, 2 ml, or 4 ml sizes, packaged in cartons.<\/p>\n\n\n\n

            STORAGE:<\/span><\/strong><\/p>\n\n\n\n

            Store in a dark, inaccessible place at temperatures ranging from 5\u00b0C to 25\u00b0C. Avoid storage with food or drinks.<\/p>\n\n\n\n

            FOR VETERINARY USE ONLY!<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

            Drops for Dogs <<PREVIOUS || NEXT>> DESCRIPTION : An oily liquid ranging from light gray to light yellow color with a distinct odor. COMPOSITION: Each 1 ml of the drug contains: CLINICAL PHARMACOLOGY Megestrol acetate, a synthetic progestogen, affects the hypothalamic-pituitary system, blocking the release of gonadotrophins (follicle-stimulating and luteinizing …<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-587","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/pages\/587","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/comments?post=587"}],"version-history":[{"count":9,"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/pages\/587\/revisions"}],"predecessor-version":[{"id":5069,"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/pages\/587\/revisions\/5069"}],"wp:attachment":[{"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/media?parent=587"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}