{"id":487,"date":"2020-07-18T11:11:51","date_gmt":"2020-07-18T11:11:51","guid":{"rendered":"https:\/\/knight-pharma.com\/web\/?page_id=487"},"modified":"2024-04-29T00:05:45","modified_gmt":"2024-04-29T00:05:45","slug":"penicillin-f","status":"publish","type":"page","link":"https:\/\/knight-pharma.com\/web\/penicillin-f\/","title":{"rendered":"PENICILLIN- F"},"content":{"rendered":"\n

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COMPOSITION: <\/span><\/strong><\/p>\n\n\n\n

1 flacon contains active substances:<\/p>\n\n\n\n

Benzathine benzylpenicillin, sterile \u2013 1 200000 units, <\/p>\n\n\n\n

Benzylpenicillin novocaine , sterile salt \u2013 300000 units.<\/p>\n\n\n\n

PHARMACOLOGICAL CHARACTERISTICS:<\/span> <\/strong><\/p>\n\n\n\n

Penicillin-F is a bactericidal antibiotic that belongs to the group of penicillins, which are sensitive to the action of \u03b2-lactamases. The medicine inhibits the formation of peptide bonds by inhibiting of transpeptidase, violates the later stages of peptidoglycan synthesis of the cell membrane, leading to lysis of cells that divide.<\/p>\n\n\n\n

Penicillin-F is active against gram-positive bacteria, including Streptococcus spp. (including Streptococcus pneumonia), Staphylococcus spp. (except penicillinase-producing), Bacillus spp., lister (L. monocytogenes), erysipelothrix (E. rhusiopathiae), most corynebacteria, and anaerobic bacteria (actinomycetes, Peptostreptococcus spp., Clostridium spp.), spirochetes (Treponema spp., Borrelia spp., Leptospira spp.). Most gram-negative bacteria, protozoa, viruses, fungi, and rickettsia are not sensitive to the medicine. Since gram-negative bacteria are sensitive to the drug only Neisseria spp., Pasteurella multocida, H. dugreyi.<\/p>\n\n\n\n

APPLICATION:<\/span> <\/strong><\/p>\n\n\n\n

Treatment of cattle, sheep, goats, pigs, horses, foxes, minks, and dogs suffering from necrobacillosis, pasteurellosis, pneumonia, mastitis, metritis, wound infection, otitis media, septicemia, cellulitis; actinomycosis, blackleg; streptococcal septicemia of cattle, sheep, and goats; horses strangles, stachybotryotoxicosis, streptococcosis, staphylococcus, infectious stomatitis, rhinitis, the plague of dogs and fur animals, swine erysipelas, and in diseases of the urinary tract, caused by micro-organisms sensitive to benzylpenicillin.<\/p>\n\n\n\n

DOSAGE<\/span><\/strong> <\/span>&<\/strong>\u00a0ADMINISTARTION<\/strong>:<\/span><\/p>\n\n\n\n

Penicillin-F Suspension prepared for injection in sterile condition immediately before the application, after we add 9 ml of isotonic sodium chloride solution or sterile water for injection or 0.25-0.5% solution of novocaine. Penicillin-F must be shaken up to a homogeneous mixture. The medicine is injected intramuscularly<\/strong> once every 10-15 days at a dose given in the table<\/p>\n\n\n\n

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CONTRAINDICATIONS<\/span><\/strong>:<\/span><\/p>\n\n\n\n

Hypersensitivity to agents of the penicillin or novocaine group. <\/p>\n\n\n\n

Do not apply to guinea pigs and hamsters. <\/p>\n\n\n\n

PRECAUTIONS:<\/span><\/strong><\/p>\n\n\n\n

Before the application of the medicine a preliminary intradermal test for tolerability should be done! <\/p>\n\n\n\n

Penicillin-F is injected only intramuscularly<\/strong>! <\/p>\n\n\n\n

Intravenous<\/strong> injection is forbidden<\/strong>!<\/p>\n\n\n\n

Penicillin-F Suspension prepared for injection in sterile condition immediately before the application. <\/p>\n\n\n\n

Meat and Milk consumption is allowed, respectively, in 20 days and 10 days after the last applications. <\/p>\n\n\n\n

Received by the deadline meat and milk utilize or feed to unproductive animals, according to a conclusion of the doctor of veterinary medicine.<\/p>\n\n\n\n

Do not mix Penicillin-F solution with other injectable solutions.<\/p>\n\n\n\n

In case of an application with bactericidal antibiotics (including cephalosporins, cycloserine, vancomycin, rifampicin, aminoglycosides) synergistic effects are observed; with bacteriostatic antibiotics (including macrolides, chloramphenicol, lincosamides, tetracycline) antagonism.<\/p>\n\n\n\n

Not recommended to combine with non-steroidal and anti-inflammatory drugs. <\/p>\n\n\n\n

Benzylpenicillin reduces clearance and increases the toxicity of methotrexate.<\/p>\n\n\n\n

PACKAGING :<\/span><\/strong> <\/p>\n\n\n\n

Bottles glass, closed by a rubber stopper under an aluminum cap, per 1 500000 UNITS.<\/p>\n\n\n\n

STORAGE:<\/span> <\/strong><\/p>\n\n\n\n

Dry, dark, unreachable for children place at a temperature from 5\u00b0C to 25\u00b0C. <\/p>\n\n\n\n

Store the medicine separately from food, drinks, including the animal feed.<\/p>\n\n\n\n

FOR VETERINARY USE ONLY!<\/strong><\/p>\n\n\n\n

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<<PREVIOUS || NEXT>> COMPOSITION: 1 flacon contains active substances: Benzathine benzylpenicillin, sterile \u2013 1 200000 units, Benzylpenicillin novocaine , sterile salt \u2013 300000 units. PHARMACOLOGICAL CHARACTERISTICS: Penicillin-F is a bactericidal antibiotic that belongs to the group of penicillins, which are sensitive to the action of \u03b2-lactamases. The medicine inhibits the …<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-487","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/pages\/487","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/comments?post=487"}],"version-history":[{"count":10,"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/pages\/487\/revisions"}],"predecessor-version":[{"id":4843,"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/pages\/487\/revisions\/4843"}],"wp:attachment":[{"href":"https:\/\/knight-pharma.com\/web\/wp-json\/wp\/v2\/media?parent=487"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}